Hi!
I have a USB remote controller with multimedia keys, this one:
Since I've upgraded to VLC 2.1.0, the Play/Pause key doesn't work anymore, or, better: if the video is stopped and I press the key, the video is played, and, if I press it again, pause doesn't work, and the play icon appears on screen; if the video is already paused, this time play doesn't work and the pause icon appears on the screen when I press it.
Guess it's a bug, because till version 2.0.9 it worked perfectly.