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./configure --enable-x11 --enable-xvideo --disable-gtk --enable-sdl --enable-ffmpeg --with-ffmpeg-mp3lame --enable-mad --enable-libdvbpsi --enable-a52 --enable-dts --enable-libmpeg2 --enable-dvdnav --enable-vorbis --enable-ogg --enable-theora --enable-faac --enable-mkv --enable-freetype --enable-fribidi --enable-speex --enable-flac --enable-caca --enable-skins --enable-skins2 --enable-alsa --disable-kde --disable-qt --enable-wxwindows --enable-ncurses --enable-release --enable-v4l --enable-x264
make
make install
vlc

And vlc running with skins2!
But I want to run VLC with wX.... Please help me!

You should use the Search function of the forums. In particular, have a look at this thread: viewtopic.php?t=14733.