In what way should I "use the global hotkeys" to allow a dedicated play/pause button on my keyboard to play/pause media in VLC when VLC is not the active window? I don't understand your suggestion.Use the global hotkeys.
What do I set it to? I can seem to get it to work (Full support, fullscreen-only, or none). All seem to click back to VLC.You can disable mouse clicks over the video, if that is what you want.
Tools -> Preferences... (Show settings: All) Video and key and mouse event handling at vout level